QUESTIONS? GOOD.

What is GlydeRX?

GlydeRX is an online telehealth platform that makes it simpler and more transparent to start GLP-1 weight loss treatment. A licensed U.S. clinician reviews your health profile, writes a prescription if appropriate, and compounded medication ships directly to your door — no insurance required, no office visits.

How is GlydeRX different from getting Ozempic through my doctor?

Brand-name GLP-1 medications like Ozempic cost $900–$1,300/month without insurance and often require prior authorization. GlydeRX offers compounded semaglutide starting at $249/month with no insurance required and clinician review typically within 24 hours. Compounded medications are not FDA-approved.

How is GlydeRX different from other online GLP-1 platforms?

GlydeRX is built around transparent pricing — costs are shown upfront before you start a questionnaire. Clinician support is included in every plan (not sold as an add-on), medication ships free with 1–2 day delivery, and there are no hidden fees or surprise charges at checkout.

What is compounded GLP-1 medication?

Compounded GLP-1 medications contain the same active ingredient as brand-name drugs like Ozempic® or Wegovy® but are prepared by state-licensed compounding pharmacies rather than pharmaceutical manufacturers. They are not FDA-approved. GlydeRX works exclusively with pharmacies that have passed rigorous independent quality inspections.

Is compounded semaglutide safe?

Compounded semaglutide is prepared by state-licensed pharmacies operating under FDA oversight and USP quality standards. GlydeRX partners only with pharmacies that have passed independent quality inspections. All prescriptions are reviewed by licensed clinicians. Compounded medications are not FDA-approved, and suitability depends on your individual health profile.

What's the difference between semaglutide and tirzepatide?

Semaglutide is a GLP-1 receptor agonist — the same active ingredient as Ozempic and Wegovy. Tirzepatide targets both GLP-1 and GIP receptors (the same mechanism as Mounjaro and Zepbound), which clinical trials suggest produces greater average weight loss. Your clinician can help determine which is appropriate for you.

Do you offer an injection-free option?

Yes. GlydeRX offers oral semaglutide starting at $279/month — a daily tablet containing the same active ingredient as injectable semaglutide, without needles. It's a good option for patients who prefer to avoid self-injection. Eligibility and appropriate dosing are determined by your clinician.

How much weight can I expect to lose on GLP-1?

Individual results vary, but clinical trial data shows meaningful average weight loss:

Semaglutide produced an average weight loss of 14.9% of body weight over 68 weeks in the STEP 1 trial.
— New England Journal of Medicine, 2021

Tirzepatide produced average losses of up to 20.9% of body weight over 72 weeks in the SURMOUNT-1 trial.
— New England Journal of Medicine, 2022

Results depend on starting weight, dosage, diet, and lifestyle. GLP-1 medications work best alongside healthy habits.

How long does it take to see results?

Most patients notice appetite changes within the first 2–4 weeks. Meaningful weight loss — typically 5% or more of body weight — usually occurs within 8–12 weeks at therapeutic doses. GLP-1 medications are designed for gradual, sustained weight loss over months, not rapid short-term results.

What are the common side effects of GLP-1 medications?

The most common side effects are nausea, vomiting, diarrhea, and constipation — particularly during the dose escalation period in the first few weeks. These typically improve as your body adjusts. Serious side effects are rare but possible. Your GlydeRX clinician will review your health history and monitor your progress throughout treatment.

Am I a good candidate for GLP-1 treatment?

You may be a candidate if you're an adult looking to lose weight and your health profile meets clinical criteria — typically a BMI of 27 or higher, or 30+ with a weight-related health condition. Eligibility is determined by a licensed clinician, not an automated system. Complete the questionnaire to find out in 24 hours.

What happens if I'm not approved?

If a clinician determines GLP-1 treatment isn't appropriate for you, you won't be charged a consultation fee. There are no automatic disqualifications — every case is reviewed individually. Your clinician may ask follow-up questions or suggest an alternative approach that better fits your health profile.

How do I get started?

Complete a 4-minute health questionnaire at glyderx.com/quiz. A licensed clinician reviews your profile — typically within 24 hours. If approved, your medication is prescribed and ships within 1–2 business days. The entire process from questionnaire to delivery takes approximately 3–5 days for most patients.

How quickly will I receive my medication?

Once a clinician approves your prescription, medication ships within 1–2 business days. Delivery time depends on your location but typically arrives 2–4 days after shipment. Shipping is free on all orders. You'll receive tracking information as soon as your order leaves the pharmacy.

What's included in my monthly plan?

Every GlydeRX plan includes your compounded medication, an initial consultation with a licensed clinician, free shipping, and ongoing clinician access throughout your treatment. There are no hidden fees — the price shown is the price you pay. Consultation, shipping, and clinician support are all included.

Do I need insurance?

No. GlydeRX is entirely self-pay. Insurance is not required and the process involves no prior authorizations or insurance denials. Pricing is shown upfront before you begin the questionnaire. Many patients use GlydeRX specifically because their insurance doesn't cover GLP-1 medications.

Can I use my HSA or FSA?

Yes. GlydeRX is HSA and FSA eligible. You can pay for your subscription using an HSA or FSA card at checkout. If you have questions about eligibility under your specific plan, check with your HSA/FSA administrator — eligibility rules can vary slightly by plan.

Who reviews my health profile?

Every patient profile is reviewed by a licensed clinician — either a nurse practitioner or MD — in OpenLoop Health's network before any prescription is written. OpenLoop Health is a U.S.-based telehealth infrastructure provider. No prescription at GlydeRX is issued by an automated system.

Who are your pharmacy partners?

GlydeRX works with four state-licensed U.S. compounding pharmacies: RedRock Pharmacy (Utah), Health Warehouse (Kentucky), Precision Medicine (New York), and Triad Rx (Alabama). All partner pharmacies have passed independent quality inspections and operate under FDA oversight and USP compounding standards.

Can I cancel my subscription?

Yes. You can cancel at any time, for any reason, with no cancellation fees. If you cancel before your medication for the current period has been ordered, you're eligible for a refund. Once medication has been ordered for your cycle, that cycle is fulfilled before the cancellation takes effect.

Which states do you serve?

GlydeRX is available in all 50 U.S. states and Washington D.C. Some services or medications may vary by state due to local regulations. Your clinician will confirm what's available in your state during the review process.